Further illuminating matters, purpose and therapeutic efficacy of MSCs are remarkably regulated through the encompassing niche/microenvironment (Zhu et al., 2016; Mehrbani Azar et al., 2018; Tejero et al., 2019; https://bookmarkproduct.com/story18412194/5-tips-about-mesenchymal-stem-cells-mscs-you-can-use-today