Pentobarbital will decrease the extent or influence of imatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Not known. pentobarbital will reduce the extent or influence of conivaptan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. pentobarbital will reduce the level or effect of lorlatinib by affecting hepatic/intestina... https://pentobarbital-for-dog-eut74789.amoblog.com/about-reliable-source-nembutal-55994285