Below, we show that conolidine, a normal analgesic alkaloid used in classic Chinese medication, targets ACKR3, thus supplying further proof of a correlation amongst ACKR3 and pain modulation and opening option therapeutic avenues for the therapy of chronic agony. We demonstrated that, in distinction to classical opioid receptors, ACKR3 https://altbookmark.com/story21558217/what-is-conolidine-for-dummies